4-Chloro-3-pyridineboronic acid

4-Chloro-3-pyridineboronic acid - Names and Identifiers

Name	4-Chloropyridine-3-boronic acid
Synonyms	AKOS BRN-0503 3-Borono-4-chloropyridine 4-CHLORO3-PYRIDYLBORONIC ACID 4-Chloropyridine-3-boronic acid 4-CHLOROPYRIDINE-3-BORONIC ACID 4-Chloro-3-pyridineboronic acid 4-CHLOROPYRIDIN-3-YLBORONIC ACID (4-chloropyridin-3-yl)boronic aci (4-Chloropyridin-3-yl)boronic acid (4-chloro-3-pyridinyl)boronic acid boronic acid, B-(4-chloro-3-pyridinyl)-
CAS	452972-10-0
EINECS	125-856-9
InChI	InChI=1/C5H5BClNO2/c7-5-1-2-8-3-4(5)6(9)10/h1-3,9-10H

4-Chloro-3-pyridineboronic acid - Physico-chemical Properties

Molecular Formula	C5H5BClNO2
Molar Mass	157.36
Density	1.415g/cm³
Boling Point	333.983°C at 760 mmHg
Flash Point	155.788°C
Vapor Presure	0mmHg at 25°C
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.559

4-Chloro-3-pyridineboronic acid - Risk and Safety

HS Code

29333999

4-Chloro-3-pyridineboronic acid - Introduction

4-Chloropyridine-3-boronic acid is an organic compound with the chemical formula C5H5BClNO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 4-Chloropyridine-3-boronic acid is a white to pale yellow solid.
-Solubility: It can be dissolved in polar solvents such as water, alcohol and ketone.
-Stability: relatively stable at room temperature, but not heat resistant.
-Melting point: about 185-190°C.
-Density: about 1.42g/cm³.
- 4-Chloropyridine-3-boronic acid is an important organic boron compound.

Use:
- 4-Chloropyridine-3-boronic acid is often used as an important raw material for organic synthesis.
-It can be used to synthesize various organic compounds, such as pharmaceutical intermediates, pesticides, dyes and photoelectric materials.
- 4-Chloropyridine-3-boronic acid is also commonly used as a ligand in organometallic-catalyzed reactions.

Preparation Method:
-Generally, 4-Chloropyridine-3-boronic acid can be synthesized by the following steps:
1. 4-chloropyridine reacts with boric acid in an organic solvent to generate the corresponding boric acid ester.
2. Hydrolysis of boric acid ester under acidic conditions to generate 4-Chloropyridine-3-boronic acid.

Safety Information:
- 4-Chloropyridine-3-boronic acid is irritating.
-Appropriate safety precautions should be taken during operation, such as wearing gloves, protective glasses and laboratory coats.
-Unusual exposure or inhalation may cause respiratory tract irritation and eye and skin irritation.
-If an accident occurs, please seek medical assistance and bring the safety data sheet of the compound.

Last Update：2024-04-09 02:00:46